Nothing Is Certain Except Death, Taxes, and How Your Body Handles Uncertainty

Rachel Rauch • August 25, 2026

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You've probably heard the line, "Nothing is certain except death and taxes." It's usually attributed to Benjamin Franklin, who wrote it to the French scientist Jean-Baptiste Le Roy — expressing his own anxiety about not hearing from Le Roy for over a year during the chaos of the French Revolution.


Every era has its uncertainty. But is it just me, or does the world feel more uncertain lately? Maybe it's the upcoming midterm elections. Maybe it's the unrest in the Middle East. Maybe contagious viruses just feel more ominous since COVID. And then the news serves up one terrible headline after another that I wasn't even thinking about until I read it.


Maybe current events barely register for you, but you still struggle to feel safe because of something that happened to you, or to someone you love. It's hard to feel certain about anything after what you've been through. If that's you, I am truly sorry, and I lament with you in that!


Here's what's actually happening in your body: uncertainty triggers the same stress response as a real physical threat. You have a small gland in your brain called the amygdala, and it interprets ambiguity the same way it interprets danger. Your body responds accordingly — racing heart, shallow breathing, sweating, blood rushing to your limbs. At the same time, the amygdala suppresses your prefrontal cortex, which slows your thinking and makes it harder to make decisions or regulate your emotions.


Live in that state long enough, and it becomes an allostatic load on your body: chronically elevated cortisol, a suppressed immune system, more inflammation, reduced digestive capacity, and hormones out of balance. You might also notice more anxiety, more fatigue, and everyday tasks feeling like more than you can carry.


I wish we could avoid uncertainty. I think you do too. We are finite people held in the hands of an infinite God. Some days I catch myself thinking that if my life had no uncertainty, I'd be less stressed. Deep down, though, I know that's not true. No uncertainty would mean I'd know everything — including every scary thing headed my way — and that would stress me out more, not less.


So if uncertainty isn't going anywhere, how do we keep it from wrecking our bodies?


Limit your knowledge. I know that sounds backward. We have the whole internet in our pockets, and we can watch the news unfold in real time. But most of what we're consuming is about things we can't control or influence. That turns knowledge into a burden. Cut back on the things you have no say in, and focus on what's local and within your reach.


Cut your social media scroll. Comparison breeds "what if" thinking and discontentment. And the algorithms are tracking every half-second pause in your scroll, then feeding you more of exactly what stirs up your uncertainty.


Build a budget and stick to it. A budget lets you plan for what you need and prepare for the unexpected. It slows the kind of spending that feeds on uncertainty.


Cut back on caffeine and other stimulants. They stack extra stress hormones on top of what your body is already producing, keeping you stuck in an activated, wound-up state.


Write down reminders of God's faithfulness — put them where you'll see them. When Moses handed leadership over to Joshua, right before Joshua had to lead the Israelites into the Promised Land, Moses gave him this:

"It is the Lord who goes before you. He will be with you; he will not leave you or forsake you. Do not fear or be dismayed." — Deuteronomy 31:8 (ESV)

Joshua was afraid. Moses didn't hand him a plan — he reminded him who was going ahead of him. We can hold onto that same reminder.


Ask if there's a deeper root to your uncertainty. Is there a past event, or a pattern, feeding what you feel now? That can be a loaded question, and it's often easier to sort through with a counselor or therapist who can help you connect what happened then to what you're carrying now.


Uncertainty isn't going away. But we don't have to just absorb it. We can be strategic about how we handle it, and about lightening the stress load it puts on our bodies.

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